Remedicivir the most effective drug, the worst hydroxychloroquine; Find out from the results of 19 drugs and treatments- who are effective and who fail
- Do not use disinfectant to prevent corona, risk of cancer from UV rays
- In prone positioning the patient is told to lie down with a burning sensation in the abdomen which opens the lungs.
Jonathan Corum / Catherine Z. Woo / Carl Zimmer. Facing Corona in the face of modern medicine is a big challenge. Doctors and scientists around the world are engaged in the search for a vaccine. According to experts, once the coronavirus vaccine is ready, it will be the fastest vaccine program in history. Vaccines usually take up to 10 years to develop.
Some medications have had good results in the treatment of corona. There are also some drugs that have been the subject of much discussion. However, the US Health Agency FDA has not licensed any treatment, only allowed use in emergencies.
The most discussed drugs and treatment outcomes in the coronary epidemic
The drug was developed by Gilead Science. This was the first drug the FDA allowed to be used in emergencies in the case of Corona. It prevents the virus from spreading by going into the gene. Remedicivir was tested as an antiviral against Ebola and Hepatitis-C.
Preliminary data from the trial showed that the drug could reduce the hospitalization time of severe patients with corona from 15 days to 11 days. Early results in death cases have not been effective but results released in July indicate that the drug could reduce mortality in critically ill patients.
This cheap and easy drug weakens many types of immune response. Doctors have long used it to treat asthma, allergies and inflammation. In June it became the first drug to reduce mortality from corona
Research on more than 6,000 people found that dexamethasone reduced mortality in patients with ventilators by a third. So far this research has not been published in any scientific journal.
This drug can help patients who are in the early stages of coronary heart disease. The National Institutes of Health recommends the use of dexamethasone in corona treatment guidelines only for patients with oxygen and ventilator support.
Such treatment is being done the most
In patients with abdominal burns are told to sleep, which opens their lungs. This method can eliminate the need for a ventilator in patients. The benefits of treatment are currently being investigated in clinical trials.
Ventilators and respiratory support devices
Devices that help patients breathe are considered important against Sirius Respiratory Disease. Giving oxygen through a nose or mask has been shown to improve the condition of some patients. Ventilators help patients with difficulty breathing where the lungs do not heal.
Treatment whose evidence is uncertain
Favipiravir, which is formulated against influenza, prevents the genetic material of the virus from replicating. According to research conducted in March, the drug has been shown to be effective in preventing airborne coronaviruses, but large clinical trials are still pending.
Coronavirus research on EIDD-2801 cells and animals designed to treat the flu has shown good results. Its testing is left to humans.
The coronavirus must first be unlocked to get inside the cell. Scientists have developed an artificial S-2 protein. It will keep at-risk cells away from the coronavirus. The use of recombinant S-2 protein on cells has shown reliable results.
A century ago, doctors extracted plasma from the blood of patients who had recovered from the flu. These convulsant plasma contain antibodies, which help patients. Researchers are now adopting this method on coronary patients as well. The initial results of convulsant plasma have been reliable. The FDA has also approved its use for severe patients with coronavirus.
Convulsant plasma contains many types of antibodies. Some of them can attack the coronavirus while some cannot. Researchers are investigating the most effective antibodies to corona by solution.
Synthetic copies of these molecules are called monoclonal antibodies. It can be prepared extensively and patients can be injected. Safety trials for this treatment have just begun.
Interferons are usually molecules that our cells make to fight viruses. Synthetic interferon is a treatment for immune disorders. In the early stages, injecting interferon may be helpful against corona. There is also some evidence to show that molecules protect a healthy person from becoming infected.
Researchers have developed several drugs that can prevent cytokine storms. This drug is effective in arthritis and other inflammatory disorders. Many of these drugs have been shown to be helpful in coronavirus trials, but some have not been effective.
Cytosorb is an equipment that filters cytokines from the blood. Sitecoins are needed to fight diseases.
This machine can clean human blood more than 70 times in 24 hours. Following good results in Europe and China, the FDA has approved its use in emergencies.
Some types of stem cells can release molecules against inflammation. Researchers have used cytokines in the treatment of storms for years. Clinical trials of its effect against Corona are now underway. However, treatment of stem cells in the first stage did not yield good results. So it is not clear whether it will work against coronavirus.
Coronavirus can go into the lining of blood vessels. It becomes small lumps, which can cause a stroke or any serious damage. These tumors are being removed with anticoagulants. Previously it was used on heart patients. A clinical trial of the drug is underway in Corona’s case.
Treatment that was not reliable
Lopinavir and Ritonavir
The drug was approved by the FDA 20 years ago for the treatment of HIV. Recently researchers used it to treat coronavirus. Seeing that, the virus stopped replicating. However, the results of some clinical trials have not been good.
In early July, the WHO closed its trial in hospitalized corona patients.
Hydroxychloroquine and chloroquine
German chemist synthesized chloroquine as a medicine for malaria in 1930. A less toxic version, hydroxychloroquine, was then developed in 1946. The drug was later used in diseases such as lupus and rheumatoid arthritis. At the onset of the corona epidemic, scientists found that both drugs prevented corona cells from replicating.
US President Donald Trump also promoted hydroxychloroquine. The FDA also temporarily approved its use in emergencies. It was later claimed that this was done under political pressure.
When data from clinical trials came to light, it was found that hydroxychloroquine is not helpful for corona patients and healthy people. According to a large research, this drug is harmful. However the research was later withdrawn.
The WHO, the National Institutes of Health and Novartis closed the trial. The FDA has now warned that the drug could cause serious side effects to the heart and other organs.
A treatment that had false prescriptions and claims
PV or inject bleach and disinfectant
In April, President Trump advised that injecting disinfectants such as alcohol or bleach could help. Trump’s statement was rejected by health professionals and researchers around the world. According to him, injecting a disinfectant can be dangerous.
Researchers use UV light to clean surfaces and kill viruses. UV light cannot remove any disease or virus from the body. This type of radiation can damage the skin. Most skin cancers are caused by exposure to UV rays in sunlight.
The FDA has warned of legal action against those who claim that the silver product is effective against corona. Many metals have natural antimicrobial properties, but even in the case of coronavirus, no good results have been found.